Wham is designed for paired-conclusion Illumina libraries with standard insert sizes (~300bp-500bp). Wham integrates mate-pair mapping, break up go through mapping, delicate-clipping, alternate alignment and consensus sequence centered evidence to predict SV breakpoints with single-nucleotide accuracy. Wham generates a blended pileup (catalog of re
Wham clusters all of the candidate breakpoints and rounds their positions to the nearest tenth foundation pair. The situation with the highest read help is noted. Should the smooth-clipped consensus sequence is usually aligned to the putative breakpoint region using the Smith-Waterman algorithm, the breakpoint is further refined to the location wit
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